NF2 Goat Polyclonal Antibody

CAT#: AP09450PU-N

NF2 goat polyclonal antibody, Aff - Purified


USD 375.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Applications ELISA, IHC
Recommended Dilution Peptide ELISA: antibody detection limit dilution 1:32000.
Immunohistochemistry: This product has been successfully used by customers on Formalin/PFA-fixed paraffin-embedded sections of Zebrafish Brain Cortex.
Reactivities Zebrafish
Host Goat
Clonality Polyclonal
Immunogen Peptide from the internal region of the protein sequence according to NP_998116.1
Specificity This antibody detects Neurofibromin 2 (Internal).
Formulation Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
Storage Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens neurofibromin 2 (merlin) (NF2), transcript variant 1
Background Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin. Merlin is closely related to the ERM (ezrin, radixin, moesin) family of proteins. The precise funtion of Merlin is not clear. It is thought to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals. It has been implicated in cell proliferation and cellular motility.
Mutations in the NF2 gene cause neurofibromatosis type II, a condition characterised by the development of tumors in the central nervous system.
Synonyms Neurofibromin-2, NF2, SCH, Schwannomin, Schwannomerlin
Reference Data
Protein Families Druggable Genome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.