NOS1 Rabbit Polyclonal Antibody

CAT#: AP09502PU-N

NOS1 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of extracts from Rat and Mouse brain tissue using NOS1 Antibody

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  Immunofluorescence staining of methanol-fixed HeLa cells using NOS1 Antibody

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: Immunofluorescence: 1/100-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic Peptide KLH conjugated corresponding to a sequence around amino acids 850-854 (F-N-SP-V-S) derived from Human nNOS.
• Specificity: This antibody detects endogenous levels of total nNOS protein.
• Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography using epitope-specific peptide
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 160 kDa
• Gene Name: Homo sapiens nitric oxide synthase 1 (NOS1), transcript variant 1
• Database Link:
  Entrez Gene 18125 MouseEntrez Gene 24598 RatEntrez Gene 4842 Human
• Background: NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti-tumor and anti-pathogenic activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS); induciblr NOS (iNOS) or macrophage NOS (mNOS); and endothelial NOS (eNOS).
• Synonyms: bNOS, nNOS, NOS type I, Neuronal NOS, Constitutive NOS, NC-NOS

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Arginine and proline metabolism, Calcium signaling pathway, Long-term depression, Metabolic pathways, Pathways in cancer, Small cell lung cancer