Cortisol Sheep Polyclonal Antibody

CAT#: AP09688PU-L

Cortisol sheep polyclonal antibody, Ig Fraction


USD 860.00

2 Weeks*

Size
    • 1 ml

Product Images

Specifications

Product Data
Applications ELISA
Recommended Dilution ELISA: 10μg/ml.
Host Sheep
Isotype IgG
Clonality Polyclonal
Immunogen Cortisol (4)-BTG
Specificity This antibody recognizes Cortisol.
Formulation 20mM Phosphate, 150mM Sodium Chloride, pH 7.2 containing 0.09% Sodium Azide as preservative
State: Ig Fraction
State: Liquid Ig fraction prepared by Caprylic Acid and Ammonium Sulphate precipitation procedures
Concentration 9.24 mg/ml (U.V.abs @ 280nm)
Background Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
Synonyms Hydrocortisone
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.