Cortisone Sheep Polyclonal Antibody

CAT#: AP09689PU-N

Cortisone sheep polyclonal antibody, Ig Fraction

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: ELISA: 1.25μg/ml; 10 ng/ml cortisone produces 73% inhibition in a competitive ELISA, employing cortisone polyclonal antibody.
• Host: Sheep
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Cortisone-BTG
• Specificity: This antibody reacts to Cortisone.
• Formulation: 20mM Phosphate, 150mM Sodium Chloride, pH 7.2 containing 0.09% Sodium Azide as preservative
  State: Ig Fraction
  State: Liquid Ig fraction prepared by Caprylic Acid and Ammonium Sulphate precipitation procedures
• Concentration: 7.2mg/ml (U.V.abs @ 280nm)
• Background: Cortisone is a hormone. Chemically it is a corticosteroid with formula C21H28O5 and IUPAC name 17-hydroxy-11-dehydrocorticosterone. It is closely related to corticosterone.
  Cortisone and adrenaline are the main hormones released by the body as a reaction to stress. They elevate blood pressure and prepare the body for a fight or flight response.
  Cortisone is the inactive precursor molecule of the active hormone cortisol. It is activated through hydroxylation of the 11-keto-group by an enzyme called 11-beta-steroid dehydrogenase. The active form cortisol is thus sometimes referred to as hydrocortisone.
  Cortisone is sometimes used as a drug to treat a variety of ailments.
• Synonyms: 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione, 17alpha-Hydroxy-11-dehydrocorticosterone, 4-Pregnene-17alpha,21-diol-3,11,20-trione