Transglutaminase 2 (TGM2) Rabbit Polyclonal Antibody

CAT#: AP10441BT-N

Transglutaminase 2 (TGM2) rabbit polyclonal antibody, Biotin

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution:

  ELISA.
  Western Blot.

• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: A 15 residue synthetic peptide derived from specific domain of Human TG2 protein
• Specificity:

  Reacts with Human 77 kDa TGM2 protein.
  This antibody does not cross reacts with Guinea Pig or any isoformes.

• Formulation: Label: Biotin
  State: Liquid purified antibody
• Purification: Affinity Chromatography on Protein A
• Conjugation: Biotin
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 7052 Human
• Background: Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
• Synonyms: TGase C, TGase-H, Tissue transglutaminase