Avil Rabbit Polyclonal Antibody

CAT#: AP10563PU-N

Avil rabbit polyclonal antibody, Aff - Purified

Product Images

Rat Muscle; WB Suggested Anti-Avil Antibody. Titration: 1.0 ug/ml. Positive Control: Rat Muscle; Avil antibody - N-terminal region (AP10563PU-N) in Rat Muscle cells using Western Blot

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blotting (0.2 - 1.0 µg/ml)
• Reactivities: Guinea Pig, Mouse, Rabbit, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide directed towards the N-term region of rat AVIL
• Formulation: State: Aff - Purified
  State: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Purification: Purified using peptide immunoaffinity column
• Gene Name: advillin
• Database Link:
  Entrez Gene 79253 Rat
• Background: AVIL is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia. Avil is a Ca2+-regulated actin-binding protein. It may have a unique function in the morphogenesis of neuronal cells which form ganglia. It is required for SREC1-mediated regulation of neurite-like outgrowth. It plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. It is involved in the formation of long fine actin-containing filopodia-like structures in fibroblast and is required for SREC1-mediated regulation of neurite-like outgrowth. Avil plays a role in ciliogenesis.
• Synonyms: AVIL, p92