SMC2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP12303PU-N

SMC2 (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of anti-SMC2 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). SMC2 (arrow) was detected using the purified Pab (1:60 dilution).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western Blot: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SMC2.
• Specificity: This antibody detects SMC2 (C-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens structural maintenance of chromosomes 2 (SMC2), transcript variant 1
• Database Link:
  Entrez Gene 10592 Human
• Background: SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
• Synonyms: SMC protein 2, SMC-2, SMC2L1, CAP-E, Chromosome-associated protein E, XCAP-E homolog
• Note: Molecular weight: 135656 Da

Reference Data

• Protein Families: Druggable Genome