LINC02210-CRHR1 (250-263) Goat Polyclonal Antibody

CAT#: AP16661PU-N

LINC02210-CRHR1 (250-263) goat polyclonal antibody, Aff - Purified

Product Images

AP16661PU-N (5ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Specifications

Product Data

• Applications: ELISA, IF, IHC
• Recommended Dilution: Peptide ELISA: 1/1000 (Detection Limit).
  Western Blot: Preliminary experiments in human colon, duodenum and placenta lysates gave no specific signal but low background (at antibody concentration up to 1 µg/ml).
  Immunohistochemistry on Paraffin Sections: 5 µg/ml. Paraffin embedded Human Brain (Cortex).
  Immunofluorescence on Mouse Prefrontal Cortical Neurons.
• Reactivities: Bovine, Canine, Human, Mouse, Rat, Sheep
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Peptide with sequence KLYYDNEKCWFGKR from the internal region of the protein sequence according to NP_004373.2.
• Specificity: This antibody recognizes CRHR1 / CRF-R (250-263).
• Formulation: Tris saline, pH~7.3
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Stabilizer: 0.5% BSA
  Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
• Database Link:
  Entrez Gene 104909134 Human
• Background: CRF1 is a receptor for corticotropin releasing factor. It shows high affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
• Synonyms: CRHR-1, CRFR, CRFR1, CRHR, Corticotropin-releasing factor receptor 1, CRF-R, CRF1, Corticotropin-releasing hormone receptor 1, CRH-R 1