Cofilin 1 (CFL1) (N-term) Rabbit Polyclonal Antibody

CAT#: AP17209PU-N

Cofilin 1 (CFL1) (N-term) rabbit polyclonal antibody

Product Images

Western blot analysis of CFL1 Antibody (N-term) in MCF-7, Hela cell line and mouse brain tissue lysates (35 ug/lane). CFL1 (arrow) was detected using the purified Pab (2 ug/ml).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:50 - 1:100.
  ELISA: 1:1,000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human CFL1
• Specificity: This antibody detects CFL1 at N-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: cofilin 1
• Database Link:
  Entrez Gene 12631 MouseEntrez Gene 1072 Human
  UniProt ID P23528
• Background: Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.
• Synonyms: CFL1, CFL, p18
• Note: Molecular weight: 18502 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton