DIO2 (Center) Rabbit Polyclonal Antibody

CAT#: AP17989PU-N

DIO2 (Center) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of DIO2 Antibody (Center) in MCF-7 cell line lysates (35ug/lane). DIO2 (arrow) was detected using the purified Pab.

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  DIO2 Antibody staining of Formalin Fixed and Paraffin Embedded Mouse brain followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the mouse DIO2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100-1/500.
  Immunohistochemistry: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 171~200 amino acids from the Center region of Human DIO2
• Specificity: This antibody recognizes DIO2.
• Formulation: PBS with 0.09% (W/V) Sodium Azide
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography followed by peptide affinity purification.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens deiodinase, iodothyronine, type II (DIO2), transcript variant 2
• Database Link:
  Entrez Gene 1734 Human
• Background: DIO2 belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3).
• Synonyms: DIOII, ITDI2, TXDI2

Reference Data

• Protein Families: Druggable Genome