MYD88 Rabbit Polyclonal Antibody

CAT#: AP18123PU-N

MYD88 rabbit polyclonal antibody

Product Images

(LEFT) Western blot analysis of MyD88 Antibody (Center) in HepG2 cell line lysates (35ug/lane). MyD88 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of MyD88 Antibody (Center) in mouse lung tissue lysates (35ug/lane). MyD88 (arrow) was detected using the purified Pab. (2ug/ml)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the Center region of human MyD88
• Specificity: This antibody reacts to MYD88.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens myeloid differentiation primary response 88 (MYD88), transcript variant 2
• Database Link:
  Entrez Gene 17874 MouseEntrez Gene 4615 Human
• Background: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.
• Synonyms: Myeloid differentiation primary response protein MyD88

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Apoptosis, Toll-like receptor signaling pathway