Apc6 (CDC16) Rabbit Polyclonal Antibody

CAT#: AP20213PU-N

Apc6 (CDC16) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CDC16 in extracts from HuvEc cells using CDC16 / APC6 antibody (Cat.-No. AP20213PU-N.)

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  Immunohistochemical analysis of human breast carcinoma tissue (Formalin- fixed Paraffin-embedded) using CDC16 / APC6 antibody (Cat.-No. AP20213PU-N).

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunofluorescence: 1/50-1/200.
  Immunohistochemistry on Paraffin sections: 1/50-1/200.
  Western blot: 1/500-1/1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Cdc16 protein.
• Formulation: Phosphate buffered saline (PBS) with 0.05% Sodium azide, approx. pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography using epitope-specific immunogen (> 95% pur; by SDS-PAGE)
• Predicted Protein Size: ~ 72 kDa
• Gene Name: Homo sapiens cell division cycle 16 (CDC16), transcript variant 2
• Database Link:
  Entrez Gene 69957 MouseEntrez Gene 8881 Human
• Background: Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cell division cycle protein 16 homolog (CDC16) is a component of the APC (anaphase-promoting complex), which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms.
• Synonyms: ANAPC6, Cell division cycle protein 16 homolog, CDC16Hs

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis