Eph receptor A2 (EPHA2) (+EPHA3/4) Rabbit Polyclonal Antibody

CAT#: AP20225PU-N

Eph receptor A2 (EPHA2) (+EPHA3/4) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of EphA2/3/4 antibody (Cat.-No.: AP20225PU-N) in extracts from Hela cells.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunoflourescence: 1/50-1/200.
• Reactivities: Human, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of EphA2/3/4 protein.
• Formulation: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen, purity is > 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: ~ 112 kDa
• Gene Name: Homo sapiens EPH receptor A2 (EPHA2)
• Database Link:
  Entrez Gene 366492 RatEntrez Gene 1969 Human
  UniProt ID P29317
• Background: EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
• Synonyms: Ephrin type-A receptor 2, Epithelial cell kinase, Eph receptor A2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance