Eph receptor B1 (EPHB1) (+EphB2) Rabbit Polyclonal Antibody

CAT#: AP20300PU-N

Eph receptor B1 (EPHB1) (+EphB2) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of EphB1/2 antibody (Cat.-No.: AP20300PU-N) in extracts from sp20 cells.

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  Immunohistochemistry analyzes of EphB1/2 antibody (Cat.-No.: AP20300PU-N) in paraffin-embedded human brain tissue.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
  Immunofluorescence: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of EphB1/2 protein.
• Formulation: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 110 kDa
• Gene Name: Homo sapiens EPH receptor B1 (EPHB1)
• Database Link:
  Entrez Gene 24338 RatEntrez Gene 270190 MouseEntrez Gene 2047 Human
• Background: Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.
• Synonyms: EPHT2, NET, HEK6, ELK, EPH2, Ephrin type-B receptor 1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance