HNRNPC Rabbit Polyclonal Antibody

CAT#: AP20305PU-N

HNRNPC rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of hnRNP C1/2 antibody (Cat.-No.: AP20305PU-N) in extracts from HuvEc cells.

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  Immunohistochemistry analyzes of hnRNP C1/2 antibody (Cat.-No.: AP20305PU-N) in paraffin-embedded human breast carcinoma tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of hnRNP C1/2 protein.
  (region surrounding Gly256)
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 34 kDa
• Gene Name: Homo sapiens heterogeneous nuclear ribonucleoprotein C (C1/C2) (HNRNPC), transcript variant 3
• Database Link:
  Entrez Gene 15381 MouseEntrez Gene 290046 RatEntrez Gene 3183 Human
• Background: The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP C1 and C2 are encoded by one gene; the two alternatively spliced transcript variants have been described.
• Synonyms: Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1 / hnRNP C2, HNRPC

Reference Data

• Protein Pathways: Spliceosome