AF10 (MLLT10) Rabbit Polyclonal Antibody

CAT#: AP20389PU-N

AF10 (MLLT10) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of AF-10 antibody in extracts from COLO205 cells.

• 

  Western blot (WB) analysis of AF-10 antibody at 1/500 dilution. Lane 1: Hela cell lysate.v Lane 2: Mouse testis tissue lysate. Lane 3: Rat testis tissue lysate.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
  Immunofluorescence: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to amino acids 200-250 of Human AF-10.
• Specificity: This antibody detects endogenous levels of AF-10 protein.
  (region surrounding Glu237)
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% by SDS-PAGE)
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Immunoaffinity Chromatography
• Predicted Protein Size: ~ 109 kDa
• Gene Name: Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 (MLLT10), transcript variant 2
• Database Link:
  Entrez Gene 17354 MouseEntrez Gene 361285 RatEntrez Gene 8028 Human
• Background: AF10 is a putative transcription factor containing a leucine zipper motif. A t (10;11) (p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in expression of an AF10 (carboxy terminus) MLL (amino terminus) fusion protein.
• Synonyms: AF10; DKFZp686E10210; MGC75086

Reference Data

• Protein Families: Druggable Genome, Transcription Factors