GAP43 pSer41 Rabbit Polyclonal Antibody

CAT#: AP20866PU-N

GAP43 pSer41 rabbit polyclonal antibody, Aff - Purified

Specifications

Product Data

• Applications: IF
• Recommended Dilution: Immunofluorescence: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibodiy detects endogenous levels of GAP43 protein only when phosphorylated at Ser41.
• Formulation: Phosphate buffered saline (PBS) pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 38, 43 kDa
• Gene Name: Homo sapiens growth associated protein 43 (GAP43), transcript variant 2
• Database Link:
  Entrez Gene 14432 MouseEntrez Gene 29423 RatEntrez Gene 2596 Human
  UniProt ID P17677
• Background: GAP-43 (growth associated protein 43, B-50, PP46, calmodulin-binding protein P-57, neuromodulin, neuron growth-associated protein 43, protein F1 is a crucial component for regenerative response in the nervous system. It is present at high levels in neuronal growth cones during development and axonal regeneration. GAP-43 is normally produced by neurons during developmental growth and axonal regeneration, but it is also expressed in specific regions of the normal adult nervous system. The neuron-specific Elav/Hu family member, HuD, interacts with and stabilizes GAP-43 mRNA in developing neurons and leads to increased levels of GAP-43 protein.
• Synonyms: Neuromodulin