Synapsin I (SYN1) pSer9 Rabbit Polyclonal Antibody

CAT#: AP20870PU-N

Synapsin I (SYN1) pSer9 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Synapsin-1 Antibody (Cat.-No.: AP20870PU-N) in extracts from A549 cells at 1/500 dilution.

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  Immunohistochemistry analysis of Synapsin-1 Antibody (Cat.-No AP20870PU-N) in paraffin-embedded human brain tissue.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunofluorescence: 1/50-1/200.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of p-Synapsin I protein when phosphorylated at Ser9.
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
  Preservative: 15 mM Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 80 kDa
• Gene Name: Homo sapiens synapsin I (SYN1), transcript variant Ia
• Database Link:
  Entrez Gene 20964 MouseEntrez Gene 24949 RatEntrez Gene 6853 Human
  UniProt ID P17600
• Background: Synapsin I is a member of the synapsin family. Synapsins are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations of the Synapsin I gene may be associated with X linked disorders with primary neuronal degeneration such as Rett syndrome.
• Synonyms: Synapsin I, Brain protein 4.1, SYN1