Eph receptor B1 (EPHB1) (+EphB2/3/4) Rabbit Polyclonal Antibody

CAT#: AP21112PU-N

Eph receptor B1 (EPHB1) (+EphB2/3/4) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of EphB1/2/3/4 antibody (Cat.-No.: AP21112PU-N) in extracts from 3T3 cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of EphB1/2/3/4 protein.
  (region surrounding Tyr594)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 118 kDa
• Gene Name: Homo sapiens EPH receptor B1 (EPHB1)
• Database Link:
  Entrez Gene 270190 MouseEntrez Gene 2047 Human
• Background: Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.
• Synonyms: EPHT2, NET, HEK6, ELK, EPH2, Ephrin type-B receptor 1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance