Claudin 8 (CLDN8) Rabbit Polyclonal Antibody

CAT#: AP21149PU-N

Claudin 8 (CLDN8) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Claudin-8 antibody (Cat.-No.: AP21149PU-N) in extracts from Jurkat cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Claudin-8 protein.
  (region surrounding Ile118)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Predicted Protein Size: ~ 28 kDa
• Gene Name: Homo sapiens claudin 8 (CLDN8)
• Database Link:
  Entrez Gene 9073 Human
• Background: Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-8 is a multi-pass membrane protein that belongs to the claudin family. Localized to the caput and the lateral margins of principal cells, claudin-8 plays an important role in tight junction-specific obliteration of the intercellular space.
• Synonyms: UNQ779, PRO1573

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction