CENPF (3198-3210) Goat Polyclonal Antibody

CAT#: AP22486PU-N

CENPF (3198-3210) goat polyclonal antibody, Aff - Purified

Product Images

Human Kidney (formalin-fixed, paraffin-embedded) stained with CENPF antibody at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/64000.
  Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from C-term of human CENPF
• Specificity: This antibody detects CENP-F (C-term).
• Formulation: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens centromere protein F (CENPF)
• Database Link:
  Entrez Gene 1063 Human
• Background: Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation.
• Synonyms: Kinetochore protein CENPF, Mitosin, AH antigen, Centromere protein F

Reference Data

• Protein Families: Druggable Genome