RNF34 (3-14) Goat Polyclonal Antibody

CAT#: AP22488PU-N

RNF34 (3-14) goat polyclonal antibody, Aff - Purified

Product Images

Human Kidney (formalin-fixed, paraffin-embedded) stained with RNF34 antibody at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Prostate (formalin-fixed, paraffin-embedded) stained with RNF34 antibody at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/32000.
  Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Bovine, Equine, Hamster, Human, Mouse, Rabbit, Rat
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from N-term of human RNF34
• Specificity: This antibody detects RFI / RNF34 (N-term).
• Formulation: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity chromatography
• Gene Name: Homo sapiens ring finger protein 34 (RNF34), transcript variant 2
• Database Link:
  Entrez Gene 80751 MouseEntrez Gene 282845 RatEntrez Gene 80196 Human
• Background: E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis (PubMed:15069192).
• Synonyms: CARP1, CARP-1, RIFF

Reference Data

• Protein Families: Druggable Genome