RNF34 (3-14) Goat Polyclonal Antibody
Other products for "RNF34"
Specifications
Product Data | |
Applications | ELISA, IHC |
Recommended Dilution | ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 3.75 µg/ml. |
Reactivities | Bovine, Equine, Hamster, Human, Mouse, Rabbit, Rat |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Synthetic peptide from N-term of human RNF34 |
Specificity | This antibody detects RFI / RNF34 (N-term). |
Formulation | Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide State: Aff - Purified State: Liquid Ig fraction |
Concentration | 0.5 mg/ml |
Purification | Immunoaffinity chromatography |
Gene Name | Homo sapiens ring finger protein 34 (RNF34), transcript variant 2 |
Database Link | |
Background | E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis (PubMed:15069192). |
Synonyms | CARP1, CARP-1, RIFF |
Reference Data | |
Protein Families | Druggable Genome |
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