PBR (TSPO) (156-169) Goat Polyclonal Antibody

CAT#: AP22540PU-N

PBR (TSPO) (156-169) goat polyclonal antibody, Aff - Purified

Product Images

Antibody (0.1 ug/ml) staining of Human Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  Human Colon (formalin-fixed, paraffin-embedded) stained with TSPO antibody at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Kidney (formalin-fixed, paraffin-embedded) stained with TSPO antibody at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/128000.
  Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from C-term of human TSPO
• Specificity: This antibody detects TSPO / BZRP (C-term).
  It is expected to recognise one isoform (NP_000705.2) only.
• Formulation: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens translocator protein (TSPO), transcript variant PBR
• Database Link:
  Entrez Gene 706 Human
• Background: Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis.
• Synonyms: MBR, Translocator protein, Peripheral-type benzodiazepine receptor, PKBS, PBR

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction