Glucose 6 Phosphate Dehydrogenase (G6PD) (305-318) Goat Polyclonal Antibody
CAT#: AP22547PU-N
Glucose 6 Phosphate Dehydrogenase (G6PD) (305-318) goat polyclonal antibody, Aff - Purified
Other products for "G6PD"
Specifications
Product Data | |
Applications | ELISA, IHC, WB |
Recommended Dilution | ELISA: 1/8000. Immunohistochemistry on Paraffin Sections: 2.5 µg/ml. Western Blot: 1/8000, 0.1 - 0.3 µg/ml. |
Reactivities | Human, Monkey |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Synthetic peptide from an internal region (aa 305-318) of human G6PD |
Specificity | This antibody detects G6PD (aa 305-318). It is expected to recognise both reported isoforms (NP_000393.4 and NP_001035810.1). |
Formulation | Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide State: Aff - Purified State: Liquid Ig fraction |
Concentration | 0.5 mg/ml |
Purification | Immunoaffinity chromatography |
Gene Name | Homo sapiens glucose-6-phosphate dehydrogenase (G6PD), transcript variant 1 |
Database Link | |
Background | G6PD is glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. |
Synonyms | Glucose-6-phosphate 1-dehydrogenase, Glucose-6-P-Dehydrogenase |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Glutathione metabolism, Metabolic pathways, Pentose phosphate pathway |
Documents
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