Glucose 6 Phosphate Dehydrogenase (G6PD) (308-320) Goat Polyclonal Antibody

CAT#: AP22548PU-N

Glucose 6 Phosphate Dehydrogenase (G6PD) (308-320) goat polyclonal antibody, Aff - Purified

Product Images

Human Spleen (formalin-fixed, paraffin-embedded) stained with G6PD antibody at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Testis (formalin-fixed, paraffin-embedded) stained with G6PD antibody at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/32000.
  Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot: 1/32000, 0.03 - 0.1 µg/ml.
• Reactivities: Human, Monkey, Xenopus
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region (aa. 308-320) of human G6PD
• Specificity: This antibody detects G6PD at 308-320.
  It is expected to recognise both reported isoforms (NP_000393.4 and NP_001035810.1).
• Formulation: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity chromatography
• Gene Name: Homo sapiens glucose-6-phosphate dehydrogenase (G6PD), transcript variant 1
• Database Link:
  Entrez Gene 24377 RatEntrez Gene 2539 Human
• Background: G6PD is glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms.
• Synonyms: Glucose-6-phosphate 1-dehydrogenase, Glucose-6-P-Dehydrogenase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glutathione metabolism, Metabolic pathways, Pentose phosphate pathway