IRAK2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP22850PU-N

IRAK2 (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of IRAK2 in HeLa (H) and K562 (K) whole cell lysate with IRAK2 antibody (AP22850PU-N) at 2 ug/ml.

• 

  Human Liver (formalin-fixed, paraffin-embedded) stained with IRAK2 antibody AP22850PU-N at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

• 

  Human Pancreas (formalin-fixed, paraffin-embedded) stained with IRAK2 antibody AP22850PU-N at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

• 

  Human Spleen (formalin-fixed, paraffin-embedded) stained with IRAK2 antibody AP22850PU-N at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

• 

  Immunocytochemical staining of HeLa cells using IRAK2 antibody (AP22850PU-N) at 2 ug/ml.

Show all 5 images

Specifications

Product Data

• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunocytochemistry.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1 - 2 µg/ml.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: IRAK2 antibody was raised against synthetic peptide
• Specificity: This antibody reacts to Interleukin 1 Receptor-Associated Kinase 2 (IRAK2).
• Formulation: PBS containing 0.02% sodium azide.
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens interleukin 1 receptor associated kinase 2 (IRAK2)
• Database Link:
  Entrez Gene 3656 Human
• Background: IRAK2, an IRAK type protein kinase, is a signal transducer for the immune response interleukin-1 receptor (IL-1R) signaling cascade. IRAK2 also has been associated with signaling cell death, potentially via the Fas-associated death domain protein/caspase-8 apoptotic pathway. Dominant negative forms of IRAK2 attenuate IL-1R-mediated NF-kappa B activation, suggesting that IRAK-2 may serve as a therapeutic target for inhibiting IL-1-induced inflammation.
• Synonyms: IRAK-2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Apoptosis, Neurotrophin signaling pathway