GSK3 beta (GSK3B) Rabbit Polyclonal Antibody

CAT#: AP22887PU-N

GSK3 beta (GSK3B) rabbit polyclonal antibody, Purified

Product Images

• 

  Skeletal muscle, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

  Pancreas, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunofluorescence.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/1000.
• Reactivities: Bovine, Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: GSK3B antibody was raised against synthetic peptide
• Specificity: This antibody reacts to Glycogen Synthase Kinase 3, Beta (GSK3B).
• Formulation: PBS, pH 7.2 containing 50% glycerol and 0.09% azide
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens glycogen synthase kinase 3 beta (GSK3B), transcript variant 1
• Database Link:
  Entrez Gene 56637 MouseEntrez Gene 84027 RatEntrez Gene 2932 Human
• Background: Glycogen Synthase Kinase 3 beta is a GSK-3 multisubstrate serine/threonine kinase that is associated with the canonical Wnt signaling pathway, which is involved in mammalian brain regionalization. Glycogen Synthase Kinase 3 beta has been implicated in Alzheimer's Disease, when improper phosphorylation of the microtubule-associated protein Tau results in the accumulation of neurofibrillary tangles. Two alternatively spliced isoforms have been observed.
• Synonyms: GSK-3 beta, Glycogen synthase kinase-3 beta, GSK3B

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Alzheimer's disease, Axon guidance, Basal cell carcinoma, B cell receptor signaling pathway, Cell cycle, Chemokine signaling pathway, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Hedgehog signaling pathway, Insulin signaling pathway, Melanogenesis, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, T cell receptor signaling pathway, Wnt signaling pathway