SRC3 (NCOA3) (188-198) Goat Polyclonal Antibody

CAT#: AP22969PU-N

SRC3 (NCOA3) (188-198) goat polyclonal antibody, Aff - Purified

Product Images

Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Bat, Bovine, Canine, Hamster, Human, Monkey, Porcine
• Host: Goat
• Clonality: Polyclonal
• Immunogen: SPG15 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SPG15
• Specificity: This antibody reacts to an internal region of Nuclear Receptor Coactivator 3 (NCOA3).
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA and 0.02% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens nuclear receptor coactivator 3 (NCOA3), transcript variant 2
• Database Link:
  Entrez Gene 8202 Human
• Background: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
• Synonyms: NCoA-3, Nuclear receptor coactivator 3, SRC-3, Steroid receptor coactivator protein 3, TRAM-1, TRAM1, RAC-3, RAC3, AIB-1, AIB1, pCIP, ACTR, BHLHE42

Reference Data

• Protein Families: Druggable Genome, Transcription Factors