p27 KIP 1 (CDKN1B) (153-165) Goat Polyclonal Antibody
CAT#: AP23041PU-N
p27 KIP 1 (CDKN1B) (153-165) goat polyclonal antibody, Aff - Purified
Other products for "CDKN1B"
Specifications
Product Data | |
Applications | ELISA, IHC, WB |
Recommended Dilution | ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1/32000, 0.1 - 0.3 µg/ml. |
Reactivities | Human |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Synthetic peptide from an internal region of human CDKN1B |
Specificity | This antibody reacts to the internal region of CDKN1B / p27 Kip1. |
Formulation | Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | 0.5 mg/ml |
Purification | Immunoaffinity chromatography |
Gene Name | Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) |
Database Link | |
Background | Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. |
Synonyms | p27Kip1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Cell cycle, Chronic myeloid leukemia, ErbB signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer |
Documents
Product Manuals |
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