TIA1 (189-199) Goat Polyclonal Antibody

CAT#: AP23048PU-N

TIA1 (189-199) goat polyclonal antibody, Aff - Purified

Product Images

Western Blot Image: Antibody (0.1 ug/ml) staining of Jurkat cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  Immunohistochemistry Image: Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE).

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/128000.
  Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
  Western Blot: 0.1 - 0.3 µg/ml.
• Reactivities: Bat, Bovine, Canine, Chicken, Human, Monkey, Mouse, Rabbit, Rat, Xenopus
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of human TIA1
• Specificity: This antibody detects TIA1 (Internal).
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens TIA1 cytotoxic granule associated RNA binding protein (TIA1), transcript variant 1
• Database Link:
  Entrez Gene 21841 MouseEntrez Gene 312510 RatEntrez Gene 7072 Human
• Background: TIA-1 is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing.
• Synonyms: Nucleolysin TIA-1, p40-TIA-1, p15-TIA-1

Reference Data

• Protein Families: Druggable Genome