FMRP (FMR1) (594-607) Goat Polyclonal Antibody

CAT#: AP23051PU-N

FMRP (FMR1) (594-607) goat polyclonal antibody, Aff - Purified

Product Images

Western Blot Image: Antibody (0.1 ug/ml) staining of KELLY cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  Immunohistochemistry Image: Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/128000.
  Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot: 0.1 - 0.3 µg/ml.
• Reactivities: Bat, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from the internal region (near the C Terminus) of the protein sequence according to NP_002015.1
• Specificity: This antibody detects FMR1 / FMRP (C-term).
• Formulation: Tris saline, pH 7.3 containing 0.02% sodium azide as preservative and 0.5% BSA as stabilizer
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO1
• Database Link:
  Entrez Gene 14265 MouseEntrez Gene 24948 RatEntrez Gene 700138 MonkeyEntrez Gene 2332 Human
• Background: Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm.
• Synonyms: Fragile X mental retardation 1 protein, Protein FMR-1

Reference Data

• Protein Families: Druggable Genome