GABA A Receptor alpha 3 (GABRA3) (480-492) Goat Polyclonal Antibody

CAT#: AP23117PU-N

GABA A Receptor alpha 3 (GABRA3) (480-492) goat polyclonal antibody, Aff - Purified

Product Images

Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
• Reactivities: Bat, Bovine, Equine, Hamster, Human, Monkey, Mouse, Rabbit, Rat
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from C-Terminus of human GABRA3 (NP_000799.1)
• Specificity: This antibody detects GABRA3 (C-term).
• Formulation: Tris saline, pH 7.3 containing 0.02% sodium azide as preservative and 0.5% BSA as stabilizer
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens gamma-aminobutyric acid type A receptor alpha3 subunit (GABRA3)
• Database Link:
  Entrez Gene 14396 MouseEntrez Gene 24947 RatEntrez Gene 2556 Human
• Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
• Synonyms: GABRA-3, GABA A Receptor subunit alpha-3

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction