CHRNA1 Rabbit Polyclonal Antibody

CAT#: AP23320PU-N

CHRNA1 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot on Rat skeletal muscle lysis using CHRNA1 antibody.

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  Immunohistochemistry on Paraffin Sections of Rat brain using CHRNA1 antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 0.75 μg/ml.
  Immunohistochemistry on Paraffin Sections (1-2.0 μg/ml). Antigen retrieval by heat is recommended.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of Human CHRNA1, identical to the related Rat and Mouse sequence
• Specificity: Recognizes CHRNA1
• Formulation: 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal and 0.05mg Sodium Azide
  State: Aff - Purified
  State: Lyophilized purified IgG fraction
• Reconstitution Method: Restore with 0.2 ml of distilled water to yield a concentration of 0.5 mg/ml.
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody after reconstitution at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens cholinergic receptor nicotinic alpha 1 subunit (CHRNA1), transcript variant 1
• Database Link:
  Entrez Gene 11435 MouseEntrez Gene 79557 RatEntrez Gene 1134 Human
• Background: CHRNA, also termed ACHRA, is mapped on 2q24-q32.This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. (1) The protein-coding sequence of the human alpha subu gene is divided into 9 exons that correspond to different structural and functional domains of the precursor molecule. (2)
• Synonyms: CHRNA1, ACHRA, CHNRA

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane