FABP4 (C-term) Rabbit Polyclonal Antibody
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Other products for "FABP4"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | Western blot 1 μg/ml (human). Immunohistochemistry on paraffin sections 1-2 μg/ml. |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthetic peptide corresponding to a sequence at the C-terminal of human FABP4 |
Specificity | This antibody detects FABP4 (C-term). No cross reactivity with other proteins. |
Formulation | 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 State: Aff - Purified State: Lyophilized Ig fraction |
Reconstitution Method | 0.2ml of distilled water will yield a concentration of 500μg/ml. |
Purification | Immunogen affinity purified |
Storage | Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens fatty acid binding protein 4 (FABP4) |
Database Link | |
Background | Fatty acid binding proteins (FABPs) are small cytoplasmic proteins that are expressed in a highly tissue-specific manner and bind to fatty acids such as oleic and retinoic acid. Adipocyte fatty-acid-binding protein, aP2 (FABP4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. Studies in aP2-deficient mice have shown that this lipid chaperone has a significant role in several aspects of metabolic syndrome, including type 2 diabetes and atherosclerosis. It regulates allergic airway inflammation and may provide a link between fatty acid metabolism and asthma. |
Synonyms | A-FABP, Adipocyte lipid-binding protein, Fatty acid-binding protein 4 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | PPAR signaling pathway |
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