Col7a1 Mouse Polyclonal Antibody

CAT#: AP23436PU-S

Col7a1 mouse polyclonal antibody, Purified

Product Images

Immunofluorescence: AP23436PU Collagen VII antibody staining of Murine Skin Cryosection. The sections was incubated with AP23436PU followed by an appropriate secondary antibody coupled to FITC

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: Immunohistochemistry on Cryosections (Ref.2).
• Reactivities: Mouse
• Host: Mouse
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant Murine type VII Collagen (aa 757-967) GST fusion protein.
• Specificity: Recognizes Mouse type VII Collagen
  Mice from which antibody is isolated show clinical evidence of epidermolysis bullosa acquisita (EBA).
• Formulation: PBS pH 7.4
  State: Purified
  State: Lyophilized purified IgG fraction
• Reconstitution Method: Restore in aqua bidest to a concentration of 1 mg/ml.
• Purification: Protein G Chromatography
• Gene Name: Mus musculus collagen, type VII, alpha 1 (Col7a1)
• Database Link:
  Entrez Gene 12836 Mouse
• Background: Type VII collagen fibrils are composed of three identical alpha collagen chains. It's location is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in the collagen V11 gene are associated with all forms of dystrophic epidermolysis bullosa.
• Synonyms: COL7A1, Long-chain collagen, LC collagen