BRIP1 (1233-1249) Rabbit Polyclonal Antibody

CAT#: AP23949PU-N

BRIP1 (1233-1249) rabbit polyclonal antibody, Aff - Purified

Product Images

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from human BRIP1 / FANCJ, aa 1233-1249
• Specificity: This antibody reacts to BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1) at aa 1233-1249.
• Formulation: PBS containing 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: 1 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens BRCA1 interacting protein C-terminal helicase 1 (BRIP1)
• Database Link:
  Entrez Gene 83990 Human
• Background: DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.
• Synonyms: BACH1, Protein FACJ, Fanconi anemia group J protein

Reference Data

• Protein Families: Druggable Genome