TCF7 (617-631) Goat Polyclonal Antibody

CAT#: AP23981PU-N

TCF7 (617-631) goat polyclonal antibody, Aff - Purified

Product Images

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 - 7.5 µg/ml.
• Reactivities: Bat, Canine, Equine, Hamster, Human, Mouse, Porcine, Rat
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from positions 617-631 of human TCF1 (NP_000536.5)
• Specificity: This antibody reacts to HNF1 homeobox A at aa 617-631.
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens transcription factor 7 (T-cell specific, HMG-box) (TCF7), transcript variant 3
• Database Link:
  Entrez Gene 21414 MouseEntrez Gene 363595 RatEntrez Gene 6932 Human
• Background: Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.
• Synonyms: Transcription factor 7, TCF-7, T-cell factor 1, TCF-1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Melanogenesis, Pathways in cancer, Prostate cancer, Thyroid cancer, Wnt signaling pathway