VEGF Receptor 2 (KDR) (1057-1061) Rabbit Polyclonal Antibody

CAT#: AP26071PU-N

VEGF Receptor 2 (KDR) (1057-1061) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of cell lysates using VEGFR2 antibody Lane 1 and 2: Huvec cell; Lane 3 HT29 cell)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide sequence around aa. 1057~1061
• Specificity: This antibody detects endogenous levels of total VEGFR2 protein.
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Affinity-chromatography using epitope-specific peptide
• Storage: Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR)
• Database Link:
  Entrez Gene 16542 MouseEntrez Gene 3791 Human
• Background: Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
• Synonyms: VEGFR2, FLK1, KDR, VEGF Receptor 2
• Note: Molecular weight: 210/230 kDa

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, VEGF signaling pathway