VEGF Receptor 2 (KDR) (1057-1061) Rabbit Polyclonal Antibody
CAT#: AP26071PU-S
VEGF Receptor 2 (KDR) (1057-1061) rabbit polyclonal antibody, Aff - Purified
Other products for "KDR"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western blot: 1:1000. |
Reactivities | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide sequence around aa. 1057~1061 |
Specificity | This antibody detects endogenous levels of total VEGFR2 protein. |
Formulation | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Affinity-chromatography using epitope-specific peptide |
Storage | Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR) |
Database Link | |
Background | Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
Synonyms | VEGFR2, FLK1, KDR, VEGF Receptor 2 |
Note | Molecular weight: 210/230 kDa |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, VEGF signaling pathway |
Documents
Product Manuals |
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