Transglutaminase 2 (TGM2) (full length) Rabbit Polyclonal Antibody

CAT#: AP31020PU-N

Transglutaminase 2 (TGM2) (full length) rabbit polyclonal antibody, Purified

Product Images

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, IP, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Immunoprecipitation.
  Western Blot: 5 - 10 µg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant full length human TGase II
• Specificity: This antibody reacts to Transglutaminase 2 (TGM2).
• Formulation: 10mM PBS, pH 7.4 containing 0.2% BSA as stabilizer and 0.09% Sodium Azide as preservative
  State: Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens transglutaminase 2 (TGM2), transcript variant 1
• Database Link:
  Entrez Gene 21817 MouseEntrez Gene 56083 RatEntrez Gene 7052 Human
• Background: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease.
• Synonyms: TGase C, TGase-H, Tissue transglutaminase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Huntington's disease