MMP13 Rabbit Polyclonal Antibody

CAT#: AP31026PU-N

MMP13 rabbit polyclonal antibody, Purified

Product Images

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 20 µg/ml.
  Western Blot: 1/25 - 1/50, 2.5 - 5 µg/ml.
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Human recombinant MMP-13 protein
• Specificity: This antibody reacts to Matrix Metalloproteinase 13 (MMP13/Collagenase3).
• Formulation: 10mM PBS, pH 7.4 containing 0.2% BSA as stabilizer and 0.09% Sodium Azide as preservative
  State: Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens matrix metallopeptidase 13 (MMP13)
• Database Link:
  Entrez Gene 171052 RatEntrez Gene 4322 Human
• Background: MMP13 is a Metallopeptidase M10A type protease. Metalloproteinase 13/Collagenase 3 (MMP13) was originally identified in breast carcinoma and has since been documented in a variety of tumors including chondrosarcomas, basal cell carcinoma, and malignant melanoma. In addition it has been detected in inflammatory diseases such as atherosclerosis, in wound healing, and in destructive joint diseases such OA and RA. MMP13 degrades the native helix of several types of fibrillar collagen, and extracellular matrix proteins in vitro.
• Synonyms: Collagenase 3, MMP13, Matrix metalloproteinase-13
• Note: Molecular Weight: ~60kDa (pro form) and ~48kDa (active form)
  Cellular Localization: Cytoplasmic

Reference Data

• Protein Families: Druggable Genome, Protease