Apolipoprotein CIII (APOC3) (N-term) Goat Polyclonal Antibody

CAT#: AP31597PU-N

Apolipoprotein CIII (APOC3) (N-term) goat polyclonal antibody, Purified

Product Images

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/2500 - 1/20000.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/2500 - 1/20000.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: APOC3 Recombinant protein from the N-terminus
• Specificity: Apo CIII recombinant protein at N-terminus.
• Formulation: 75mM PBS, pH 7.2 containing 75 mM Sodium Chloride and 0.02% Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein G Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid freeze-thaw cycles.
• Stability: Shelf life: one year from despatch
• Gene Name: Homo sapiens apolipoprotein C3 (APOC3)
• Database Link:
  Entrez Gene 345 Human
• Background: Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.
• Synonyms: Apolipoprotein C-III, Apolipoprotein C3, Apo-CIII, ApoC-III

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: PPAR signaling pathway