Cathepsin V (CTSV) Rabbit Polyclonal Antibody

CAT#: AP31627PU-N

Cathepsin V (CTSV) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of extracts from 293/COS cells, treated with etoposide 25uM 1h, using CATL2 (Cleaved-Leu114) Antibody. The lane on the right is treated with the synthesized peptide.

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  Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/20000.
  Immunohistochemistry on Paraffin Sections: 1/200.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from human CATL2.
• Specificity: This antibody detects endogenous levels of of fragment of activated CATL2 resulting from cleavage adjacent to Leu114.
• Formulation: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody (in aliquots) at -20°C or lower.
  Avoid freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens cathepsin V (CTSV), transcript variant 2
• Database Link:
  Entrez Gene 1515 Human
• Background: Cathepsin V, also known as Cathepsin L2 and Cathepsin U, is a cysteine protease of the papain family. It is expressed as a proenzyme in lysosomes, which can be autocatalytically converted to the mature form at pH 4.0. Cathepsin V is specifically expressed in the thymus, testis, and corneal epithelium.
• Synonyms: Cathepsin V, Cathepsin U, CTSL2, CATL2, CTSU, CTSV

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome