5HT3E (HTR3E) (Center) Rabbit Polyclonal Antibody

CAT#: AP50002PU-N

5HT3E (HTR3E) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

5HT3E Antibody (Center) western blot analysis in CEM cell line lysates (35 ug/lane).This demonstrates the 5HT3E antibody detected the 5HT3E protein (arrow)

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  5HT3E Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500
  Flow Cytometry: 1/10 - 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 133-162 amino acids from the Central region of human 5HT3E.
• Specificity: This antibody reacts to Serotonin receptor 3E.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens 5-hydroxytryptamine receptor 3E (HTR3E), transcript variant 1
• Database Link:
  Entrez Gene 285242 Human
• Background: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. HTR3E encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
• Synonyms: 5-hydroxytryptamine receptor 3E, 5-HT3E
• Note: Molecular Weight: 51438 Da

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane