Acrosin (ACR) (C-term) Rabbit Polyclonal Antibody
Other products for "ACR"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1/1000. Western blotting: 1/50-1/100. Immunohistochemistry on Paraffin Sections: 1/50-1/100. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 392~421 amino acids from the C-terminal region of Human ACR |
Specificity | This antibody recognizes Acrosin (C-term). |
Formulation | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide |
Concentration | lot specific |
Purification | Saturated Ammonium Sulfate (SAS) precipitation |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens acrosin (ACR) |
Database Link | |
Background | ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. |
Synonyms | acrosin; ACRS; preproacrosin; proacrosin |
Note | Molecular Weight: 45847 Da |
Reference Data | |
Protein Families | Druggable Genome, Protease |
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