ACTR1A (Center) Rabbit Polyclonal Antibody

CAT#: AP50073PU-N

ACTR1A (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

ACTR1A Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the ACTR1A antibody detected the ACTR1A protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human ACTR1A
• Specificity: This antibody reacts to Centractin alpha.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ARP1 actin-related protein 1 homolog A, centractin alpha (ACTR1A)
• Database Link:
  Entrez Gene 54130 MouseEntrez Gene 10121 Human
• Background: This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
• Synonyms: ACTR1A, CTRN1, ARP1
• Note: Molecular Weight: 42614 Da