ACTR1A (Center) Rabbit Polyclonal Antibody
Other products for "ACTR1A"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1000. Western blotting: 1/100 - 1/500. |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human ACTR1A |
Specificity | This antibody reacts to Centractin alpha. |
Formulation | PBS containing 0.09% (W/V) sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens ARP1 actin-related protein 1 homolog A, centractin alpha (ACTR1A) |
Database Link | |
Background | This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. |
Synonyms | ACTR1A, CTRN1, ARP1 |
Note | Molecular Weight: 42614 Da |
Reference Data |
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