AMID (AIFM2) (C-term) Rabbit Polyclonal Antibody

CAT#: AP50123PU-N

AMID (AIFM2) (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of AIFM2 Antibody (C-term) in mouse liver tissue lysates (35 ug/lane). AIFM2 (arrow) was detected using the purified Pab.

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  Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with AIFM2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

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  AIFM2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/50 - 1/100.
  Flow Cytometry: 1/10 - 1/50.
  Immunohistochemistry: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 326~356 amino acids from the C-terminal region of human AIFM2
• Specificity: This antibody reacts to AIF2.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens apoptosis inducing factor, mitochondria associated 2 (AIFM2), transcript variant 1
• Database Link:
  Entrez Gene 84883 Human
• Background: AIFM2 is significant homology to NADH oxidoreductases and the apoptosis-inducing factor PDCD8/AIF. The protein has been shown to induce apoptosis. This protein is found to be induced by tumor suppressor protein p53 in colon caner cells.
• Synonyms: Apoptosis-inducing factor 2, AMID, PRG3
• Note: Molecular Weight: 40527 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane