bcl 6 (BCL6) (C-term) Rabbit Polyclonal Antibody

CAT#: AP50359PU-N

bcl 6 (BCL6) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

BCL6 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the BCL6 antibody detected the BCL6 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 675-704 amino acids from the C-terminal region of human BCL6
• Specificity: This antibody reacts to Bcl-6.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens B-cell CLL/lymphoma 6 (BCL6), transcript variant 2
• Database Link:
  Entrez Gene 604 Human
• Background: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
• Synonyms: BCL6, BCL5, BCL-5, LAZ3, LAZ-3, ZBTB27, ZNF51
• Note: Molecular Weight: 78846 Da

Reference Data

• Protein Families: Druggable Genome, Transcription Factors