CBX8 (Center) Rabbit Polyclonal Antibody

CAT#: AP50746PU-N

CBX8 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

CBX8 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the CBX8 antibody detected the CBX8 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 160-189 amino acids from the Central region of human CBX8
• Specificity: This antibody reacts to CBX8.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 43396 Da
• Gene Name: Homo sapiens chromobox 8 (CBX8)
• Database Link:
  Entrez Gene 30951 MouseEntrez Gene 57332 Human
• Background: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
• Synonyms: Chromobox protein homolog 8, Polycomb 3 homolog, Rectachrome 1, PC3, RC1

Reference Data

• Protein Families: Transcription Factors