CHRND (Center) Rabbit Polyclonal Antibody

CAT#: AP50909PU-N

CHRND (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

CHRND Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CHRND antibody detected the CHRND protein (arrow).

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  CHRND Antibody (Center) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
  Flow Cytometry: 1/10 - 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 175-204 amino acids from the Central region of human CHRND
• Specificity: This antibody reacts to CHRND.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 58895 Da
• Gene Name: Homo sapiens cholinergic receptor nicotinic delta subunit (CHRND), transcript variant 1
• Database Link:
  Entrez Gene 1144 Human
• Background: The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
• Synonyms: CHRND, ACHRD

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane